n Italy, as of February 18, the prevalence of the so-called ‘English variant’ of the Sars-CoV-2 virus was 54.0%, with values ranging between 0% and 93.3% in the different regions, while for the ‘Brazilian’ one was 4.3% (0% -36.2%) and for the ‘South African’ one was 0.4% (0% -2.9%). For the investigation, the laboratories of the Regions and Autonomous Provinces were asked to select subsamples of positive cases and to sequence the genome of the virus, according to the procedures described in the circular of the Ministry of Health of February 17.